HumanCD4+TCell.ImagecourtesyofNIAID.
Tcellsareregulatorsoftheimmunesystem.CD4+TcellsarealsoknownashelperTcellsbecausetheyactonothercellsoftheimmunesystemtopromotevariousaspectsoftheimmuneresponse,includingimmunoglobulinisotypeswitchingandaffinitymaturationoftheantibodyresponse,macrophageactivationandenhancedactivityofnaturalkillercellsandcytotoxicTcells.
CellsYouCanCountontoPerform
LonzaCD4+TCellsareisolatedfromperipheralbloodofhealthydonors.Briefly,mononuclearcells(MNCsorPBMCs)areisolatedfromapheresisderivedperipheralbloodandarefurtherpurifiedviaimmunomagneticselectiondirectedagainstCD4.
CryopreservedCD4+Tcellsareguaranteed≥90%pureforCD4+Tcells,asassessedbyflowcytometry.Theyareguaranteedtocontain≥10millionviablecellspervial.HIV-1,hepatitisBandhepatitisCarenotdetectedforalldonorsand/orcelllots.ACertificateofAnalysisisprovidedforeachcelllotpurchased.
Cellsareavailablefrommultipledonors.PleasecontactCustomerServicefordetailsonavailableinventoryanddonordemographiccharacteristics(age,gender,andethnicity).
WhitePaper:Th17CellDifferentiation Th17cellsarestartingtocomeintothespotlightforpotentialimmunotherapytreatments.OneofthemajorchallengesinstudyingTh17cellularactionsisobtainingenoughcellsforanygivenexperiment.ReadthiswhitepapertolearnaboutarobustmethodtodifferentiateperipheralbloodCD4+TcellsintofunctionalTh17cellsusingabead-basedactivationtechnology. | DownloadWhitepaper |
ChoicesinCellTypeandTissueSource
Hematopoieticandimmuneresearchrequirescellsfromdifferentdonorsandtissuesources.That"swhyLonzaoffersmanydifferentperipheralbloodcelltypes.Ifyouneeddifferentcelltypesfromthesamedonor,youcaneitherisolatefromLonzacryopreservedPBMCsorcontactCustomerServicetoinquireaboutcellsmatchedfromthesamedonor.
Inaddition,ifyouareinterestedinmorenaiveTcells,unprocessedbonemarrow,autologousbonemarrowandwholebloodfromthesamedonor,bonemarrowCD34+cells,orcordbloodCD34+cellsmightbegoodsolutions.
SupportedbyLonzaMedia
LGM-3™LymphocyteGrowthMediumisrecommendedforoptimalperformance.PleasecontactScientificSupportforthawingandculturingguidance.
LonzaguaranteestheperformanceofClonetics™/Poietics™cellsonlyifappropriateClonetics™/Poietics™mediaandreagentsareusedexclusivelyandtherecommendedstorageanduseprotocolsarefollowed.Anymodificationsmadetotherecommendedcellsystemsincludingtheuseofalternativemedia,reagentsorprotocols,willvoidcellandmediaperformanceguarantees.Ifyouneedassistanceinselectingtheappropriatemedia,reagents,orprotocol,pleasecontactLonzaScientificSupport.
龙沙生物技术有限公司于2019年05月10日成立。法定代表人David Johann Wach,公司经营范围包括:生物技术开发服务(我国稀有和特有的珍贵优良品种,国家保护的原产于我国的野生动、植物资源开发除外);生物技术推广服务(我国稀有和特有的珍贵优良品种,国家保护的原产于我国的野生动、植物资源开发除外);生物技术咨询、交流服务(我国稀有和特有的珍贵优良品种,国家保护的原产于我国的野生动、植物资源开发除外);生物技术转让服务(我国稀有和特有的珍贵优良品种,国家保护的原产于我国的野生动、植物资源开发除外);医学研究和试验发展(人体干细胞、基因诊断与治疗技术除外);药品研发(人体干细胞、基因诊断与治疗技术除外);货物进出口(涉及外资准入特别管理规定和许可审批的商品除外);技术进出口;贸易代理;商品批发贸易(涉及外资准入特别管理规定和许可审批的商品除外);生物药品制造;化学药品原料药制造;化学药品制剂制造等。