Lonza/Hepatocytes & Media/HUCPI/1 Ea,Lonza,,Lonza,龙沙,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Lonza/Hepatocytes & Media/HUCPI/1 Ea

产品编号：HUCPI

市场价：¥0.00

场地：美国(厂家直采)

产品分类：细胞相关>细胞培养>培养基>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：待定

品牌： Lonza

公司：Lonza

公司分类：

商品介绍

FreshHumanHepatocytes

TriangleResearchLaboratories(TRL),nowpartofLonza,providesfreshhumanhepatocytesisolatedfromwholeandresectedlivertissues.TheavailABIlityofthesetissuesisdifficulttopredict.Ifyouwouldliketobenotifiedoffreshhumanhepatocyteisolations,pleasesignupforourFreshAlertlist.

Primaryfreshhumanhepatocytescanbeusedforavarietyofinvitroapplications,including,butnotlimitedto:

Metabolism
Drug-druginteraction
Drugtransporteractivity
Toxicityofdrugcandidates

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CryopreservedHumanHepatocytes

Everylotofhumancryopreservedhepatocytesischaracterizedforpost-thawviabilityandyield,plateability(adherencetoacollagen-coatedsurface),andsomecombinationofPhaseIandPhaseIIdrugmetabolizingenzymeactivities,inducibility,anduptakeandeffluxtransporteractivity—documentedinacertificateofanalysis.Wehaveawideselectionoflotsthatcanbeusedforavarietyofapplications,including,butnotlimitedto:

Drugmetabolizingenzymeactivity(stability,clearance,speciescomparison,metaboliteprofilingandID)
SUSPensiondrugtransporteruptake
Time-dependentmetabolism(platedassayforlow-clearancecompounds)
CYP450Induction(mRNAandactivity)
Plateddrugtransporterassays(uptakeandefflux)
Toxicityassays

AllsuspensionqualifiedhumancryopreservedhepatocytesarecharacterizedforCYP450andPhaseIIdrug-metabolizingenzymeactivity.Bothsingledonorandpooledhumancryopreservedhepatocytescanbeusedforavarietyofapplicationsincludingmetabolicstability,intrinsicclearance,metaboliteID,metaboliteprofiling,speciescomparisonstudies,anduptaketransporterstudies.

Webinar:

MaximizingTheUtilityOfPrimaryHumanHepatocytesInTheDrugDevelopmentPipeline

Dr. Salman Khetani, University of Chicago

Dr.SalmanKhetanidiscussesvariousprimaryhepatocytesmodelsinthedrugdevelopmentpipeline.

>WatchtheArchivedWebinar

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CryopreservedHumanHepatocytesforPlatedApplications

CryopreservedHumanHepatocytes,Plateable,MetabolismQualified
Usedformultipleapplications,includingthestudyoflow-clearancecompoundmetabolism.EachlotistestedformetabolicactivityofCYP2C9,CYP2D6,andCYP3A4.Theselotsareguaranteedplateableforaminimumof3daysinculture.
CryopreservedHumanHepatocytes,Plateable,InductionQualified
Usedforavarietyofapplications,includingtodetermineifcompoundsofinterestareinducersofCYP1A2,CYP2B6,and/orCYP3A4.QualificationincludestestinginductionofeachisoformwithaknowninducerandmeasuringthefoldchangeinmRNAexpressionandactivity.Theselotsareguaranteedplateableforaminimumof5daysinculture.
CryopreservedHumanHepatocytes,Plateable,TransporterCertified™
UsedformultipleapplicationsincludinguptakeandeffluxtransporterassayssuchasfacilitatedactiveuptakeandB-Clear™.Theselotsdemonstratetransporteruptakeandeffluxactivitysimilartofreshhumanhepatocytes.QualystTransporterSolutionscharacterizesthesecellsasexpertsinthehepatictransporterfield.Theselotsareguaranteedplateableforaminimumof7daysinculture.

Interestedincustomcells?Learnaboutcustomcellpreparationoptions.

RelatedProducts:IntestinalCells,RenalCells,LungCells,Neurons, DermalCells

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品牌介绍

龙沙生物技术有限公司于2019年05月10日成立。法定代表人David Johann Wach，公司经营范围包括：生物技术开发服务（我国稀有和特有的珍贵优良品种，国家保护的原产于我国的野生动、植物资源开发除外）;生物技术推广服务（我国稀有和特有的珍贵优良品种，国家保护的原产于我国的野生动、植物资源开发除外）;生物技术咨询、交流服务（我国稀有和特有的珍贵优良品种，国家保护的原产于我国的野生动、植物资源开发除外）;生物技术转让服务（我国稀有和特有的珍贵优良品种，国家保护的原产于我国的野生动、植物资源开发除外）;医学研究和试验发展（人体干细胞、基因诊断与治疗技术除外）;药品研发（人体干细胞、基因诊断与治疗技术除外）;货物进出口(涉及外资准入特别管理规定和许可审批的商品除外);技术进出口;贸易代理;商品批发贸易（涉及外资准入特别管理规定和许可审批的商品除外）;生物药品制造;化学药品原料药制造;化学药品制剂制造等。

公司介绍

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Classical Media Human Primary Cells and Media Hepatocytes/ADMETox Hematopoietic and Immune Cells

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